The Science

Our most well-respected scientific research validates the time-honored understanding that by far and away the most powerful factors affecting health and longevity are modifiable choices including the foods we eat and other aspects of lifestyle. So let’s move forward and explore this empowering information.

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Risk Factors Associated With Alzheimer Disease and Related Dementias by Sex and Race and Ethnicity in the US

JAMA • May 9, 2022

Association Between Physical Activity and Risk of Disabling Dementia in Japan

JAMA • March 29, 2022

Association of Life’s Simple 7 with incident dementia and its modification by the apolipoprotein E genotype

Alzheimer’s Dementia • January 14, 2022

Association of Physical Activity Level With Risk of Dementia in a Nationwide Cohort in Korea

JAMA • December 16, 2021

Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study

BMJ • December 15, 2021

Higher Coffee Consumption Is Associated With Slower Cognitive Decline and Less Cerebral Aβ-Amyloid Accumulation Over 126 Months: Data From the Australian Imaging, Biomarkers, and Lifestyle Study

Frontiers in Aging Neuroscience • November 19, 2021

Neuropsychological, neuropsychiatric, and quality-of-life assessments in Alzheimer’s disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study

Alzheimer’s & Dementia • November 2, 2021

Targeting whole body metabolism and mitochondrial bioenergetics in the drug development for Alzheimer’s disease

Acta Pharmaceutica Sinica B • June 16, 2021

Precision Medicine Approach to Alzheimer’s Disease: Successful Proof-of-Concept Trial

Preprint • May 11, 2021

Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age

Neurology • May 5, 2021

Obesity is associated with reduced cerebral blood flow – modified by physical activity

Neurobiology of Aging • April 22, 2021

Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease

Alzheimer’s Research & Therapy • February 23, 2021

Association of Cognitive Function Trajectories in Centenarians With Postmortem Neuropathology, Physical Health, and Other Risk Factors for Cognitive Decline

JAMA Network Open • January 15, 2021

Porphyromonas gingivalis is a Strong Risk Factor for Alzheimer’s Disease

Journal of Alzheimer’s Disease • November 11, 2020

Anti-inflammatory treatment rescues memory deficits during aging in nfkb1−/− mice

Aging Cell • September 11, 2020

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