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Publication

Journal of the American Medical Association

Author(s)

Yu Zhang, Yuxi Liu, and Yanping Li

Abstract

Question: Is long-term intake of caffeinated and decaffeinated coffee associated with risk of dementia and cognitive outcomes? Findings: In this prospective cohort study of 131,821 individuals from 2 cohorts with up to 43 years of follow-up, 11,033 dementia cases were documented. Higher caffeinated coffee intake was significantly associated with lower risk of dementia. Decaffeinated coffee intake was not significantly associated with dementia risk.

Date

February 9, 2026

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