How Sweeteners Are Reshaping Your Gut Bacteria

How Sweeteners Are Reshaping Your Gut Bacteria
By Team Perlmutter
Category: Food

My recent blog revealing a profound increased risk for developing diabetes in people who consume artificially sweetened beverages clearly struck a note, and with good reason. These days we are being heavily lobbied by beverage manufacturers to rethink our position on sugar sweetened beverages, no doubt because of the ever expanding medical literature that indicates that these dietary choices are profoundly threatening to our health.

In comparing risk for diabetes in individuals consuming artificially sweetened beverages compared to sugar sweetened beverages, there was actually a profound increased risk for diabetes in those consuming artificially sweetened drinks. Clearly, this seems counterintuitive. But now, new research is actually revealing the mechanism by which this actually occurs.

In a series of elegant experiments, Israeli researchers have demonstrated, in laboratory animals and humans, that the effect of artificial sweeteners on changing the gut bacteria has a profound role in changing metabolism, especially the metabolism of sugar. These researchers have been able to induce diabetes in laboratory animals at will, simply by feeding them artificially sweetened foods. They then were able to characterize the changes in the gut bacteria. Even more profound was their research that demonstrated that by taking fecal specimens from the animal that had been exposed to artificial sweeteners like aspartame, and transplanting these fecal specimens into laboratory animals that did not have gut bacteria, the risk for diabetes was also increased.

If that wasn’t compelling enough, they then showed that similar changes occur in human gut bacteria when humans consume artificial sweetener, as well as the fact that these changes in the gut bacteria relate to metabolic changes that pave the way for diabetes.

Over the next few years we’re going to see more and more advertising for artificially sweetened beverages as the news related to the dangers of sugar sweetened beverages gets more traction. But clearly, this should in no way be interpreted as giving the green light for artificially sweetened beverages as we know see really good science demonstrating that risk or some of our most devastating medical conditions is actually even higher with these foods are consumed.

Finally, just so there’s no misunderstanding, my purpose in presenting this information is not to have you reach the conclusion that drinking sugar sweetened beverages is the right choice! And aside from soda, it’s important to recognize that even fruit juice is high in sugar with a 12 ounce glass of orange juice containing 36g of carbohydrates which translates to 9 teaspoons of sugar.

Related Topics

Artificial Sweeteners  Gut Microbiome  Gut Microflora  Sugar  Diabetes  

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Mark Hyman, MD