Coffee and Dementia Risk Reduction
A major new study published in JAMA followed more than 131,000 men and women for up to 43 years and offers reassuring news for coffee drinkers. Researchers looked at long-term consumption of caffeinated coffee, decaffeinated coffee, tea, and total caffeine intake. Over the decades of follow-up, more than 11,000 cases of dementia were recorded.
Here’s the key takeaway: people who drank caffeinated coffee had a lower risk of developing dementia. Those in the highest intake group had about an 18 percent lower risk compared to those who drank little or none. Tea drinkers showed similar benefits. Decaffeinated coffee, however, did not show the same protective association.
The sweet spot appeared to be about two to three cups of caffeinated coffee per day, roughly 300 milligrams of caffeine. Drinking more than that did not seem to add extra benefit. In other words, moderate intake was best.
The researchers also looked at earlier stages of cognitive change. People who drank more caffeinated coffee were less likely to report memory complaints and performed slightly better on cognitive testing. The improvements were modest, but consistent.
Why might caffeinated coffee help? The simplest explanation is caffeine. Caffeine stimulates the brain in ways that may help protect nerve cells over time. It has been linked to lower levels of brain inflammation, better blood flow, and improved blood sugar control. Since inflammation, poor circulation, and insulin resistance are all connected to dementia risk, this could help explain the findings.
But coffee is more than caffeine. It is one of the richest sources of antioxidants in the modern diet. These natural plant compounds, especially chlorogenic acids, help neutralize oxidative stress and support healthy blood vessels. Oxidative stress and vascular problems both play a role in age-related cognitive decline.
The fact that decaf did not show the same benefit suggests caffeine plays an important role. However, it is also possible that people switch to decaf because of existing health issues, which could influence results. As with any observational study, this research shows association, not proof of cause and effect. Still, the findings fit with many previous studies pointing in the same direction.
If coffee is part of your daily routine, quality matters. Choose organic coffee whenever possible. Coffee is one of the most heavily sprayed crops in the world, and organic options reduce pesticide exposure. Look for brands that test for mold and mycotoxins like Purity Coffee. Poor storage conditions can allow mold growth on beans, and while levels are usually regulated, lower exposure is always preferable when something is consumed daily.
Roast level also influences nutritional content. Lighter roasts tend to preserve more of the natural antioxidants found in coffee beans. Dark roasts have their own unique flavor and compounds, but some antioxidant levels decline with heavy roasting. Brewing method matters as well. Paper filters remove certain oily compounds that can raise LDL cholesterol in some individuals.
It is also important to remember that more is not better. Excess caffeine can interfere with sleep, increase anxiety, and stress the nervous system. Poor sleep itself is strongly linked to cognitive decline. That is one reason moderate intake appears to be the optimal range.
For most people, two to three cups of high-quality, organic, mold-tested coffee per day fits comfortably within what this study suggests is beneficial. Individual differences still matter. People who are sensitive to caffeine, struggle with sleep, or have heart rhythm issues may need to limit intake.
But for many individuals, that morning cup of coffee may be doing more than boosting energy and focus. It may be quietly supporting long-term brain health as part of an overall lifestyle that includes good sleep, regular exercise, and a nutrient-dense diet.
If you’re looking for a clean, organic, mold-tested option that prioritizes antioxidant content and rigorous quality standards, my go-to is PURITY COFFEE. If you’d like to try it out, you’ll receive 30% off when you use my link here.

