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In Brain Defenders, David Perlmutter, MD, introduces a revolutionary understanding of neurodegenerative dise...
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David Perlmutter, MD
Meet America’s Neurologist™
The Latest
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Carb Content of Common Foods
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Gluten-Associated Cross-Reactive Foods
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Resources
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Books
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Brain Defenders
Drop Acid
Brain Maker
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The Grain Brain Whole Life Plan
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About
Meet Dr. David Perlmutter
Meet Dr. Austin Perlmutter
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Blog
March 10, 2026
Breathing CO2 to Boost Brain Detox? What the Latest Study Reveals
A fascinating new study explores a topic I have written about many times before: the brain’s waste clearance system, known as the glymphatic system. As I have discussed in previous blogs, one of the most imp…
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Alzheimer’s Prevention Strategies Validated
Top Researchers Reveal How Gluten Threatens Health
Food Choices Change Our Gene Expression
March 5, 2026
Cheese Consumption Linked to Lower Dementia Risk
A 25-year prospective analysis from the Malmö Diet and Cancer cohort evaluated the associations between high-fat and low-fat dairy intake and incident dementia in 27,670 Swedish adults. Dietary assessment co…
February 26, 2026
Can the Mediterranean Diet Help Prevent Stroke in Women?
A recent meta-analysis published in Neurology offers encouraging news: women who closely follow a Mediterranean-style diet appear to have about a 12 percent lower risk of stroke. That finding is important…
February 24, 2026
Coffee and Dementia Risk Reduction
A major new study published in JAMA followed more than 131,000 men and women for up to 43 years and offers reassuring news for coffee drinkers. Researchers looked at long-term consumption of caffeinated coff…
February 20, 2026
What the Nile Reveals About Modern Metabolic Health
I’m writing this blog while cruising south (upstream) on the Nile River, watching the shoreline drift by in its slow, ancient rhythm. It is impossible to be here and not feel the weight of history. This rive…
January 14, 2026
Dr. Perlmutter’s Views on the 2025–2030 Dietary Guidelines for Americans
For decades, federal dietary guidance has struggled to keep pace with what clinicians and researchers have observed on the front lines of chronic disease. The newly released Dietary Guidelines for Americans,…
January 12, 2026
Why Berberine Earned a Place in My Daily Supplement Stack
When people ask me about supplements, I always come back to one foundational principle: if it doesn’t meaningfully improve metabolic health, it probably doesn’t belong in my routine. That’s exactly why berbe…
December 23, 2025
The Brain’s Immune System and a Breakthrough That Changes Everything
In my recent lectures, podcasts, and blog posts, I’ve been emphasizing a message that is still surprisingly new to many people: the health of the brain is inseparable from the health of its immune system. At…
December 3, 2025
Why Redefining Alzheimer’s as a “Biological” Condition Is Harmful, and Why the International Working Group Is Pushing Back
In late 2024, the Alzheimer’s Association (AA) introduced new diagnostic criteria suggesting that Alzheimer’s disease can be identified in people who are completely cognitively normal, solely on the basis of…
December 1, 2025
Can Coffee Actually Reduce Atrial Fibrillation Recurrence?
A New Randomized Trial Says Yes. For decades, patients with atrial fibrillation (AF) have been told that caffeine is a trigger for arrhythmias. Many clinicians have reinforced this idea, urging patients to …
November 27, 2025
Pickleball – Know the Risks Before You Play
Pickleball has certainly become a thing. It’s the perfect blend of fun, movement, and social engagement, especially in retirement communities like where I live. One player captured the appeal succinctly in a…
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