The Science

Our most well-respected scientific research validates the time-honored understanding that by far and away the most powerful factors affecting health and longevity are modifiable choices including the foods we eat and other aspects of lifestyle. So let’s move forward and explore this empowering information.

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MORE PUBLICATIONS

Therapeutic Potential of Ketone Bodies for Patients With Cardiovascular Disease

Journal of the American College of Cardiology • April 6, 2021

The Mechanisms by Which the Ketone Body D-β-Hydroxybutyrate May Improve the Multiple Cellular Pathologies of Parkinson’s Disease

Frontiers in Nutrition • May 14, 2019

Low-Fat Versus Ketogenic Diet in Parkinson’s Disease: A Pilot Randomized Controlled Trial

Movement Disorders • March 5, 2018

Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer’s Disease Risk Reduction and Early Intervention

July 25, 2018

The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer

Nutrition & Metabolism • March 11, 2015

Dietary Interventions in Autism

Autism Spectrum Disorders – From Genes to Environment • August 1, 2011

Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature

Nutrition and Metabolism • February 26, 2009

Is there a role for carbohydrate restriction in the treatment and prevention of cancer?

Journal of Nutrition and Metabolism • October 26, 2011

Dietary treatment in adults with refractory epilepsy

Neurology • October 29, 2014

Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease

Natural Medicine • March 21, 2015

A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome

PNAS • November 20, 2016

Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder

PLOS Genetics • October 28, 2016

An Evolutionary and Mechanistic Perspective on Dietary Carbohydrate Restriction in Cancer Prevention

Journal of Evolution and Health • September 20, 2016

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

September 5, 2017

Dietary ketosis enhances memory in mild cognitive impairment

Neurobiology of Aging • September 10, 2010

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